Liquid filling and controlled glass-neck flame sealing for approved open glass ampoules and compatible pharmaceutical or specialty liquids.
For a quote, send ampoule drawings, the liquid and fill volume, required ampoules per minute, gas and burner utilities, seal and inspection requirements. We supply within India only and respond within 1 day.
Machine overview
H M Pharma Machines manufactures ampoule filling and sealing equipment in Ahmedabad, Gujarat, India. Open glass ampoules are held upright for liquid dosing, then move through regulated neck preheating and flame sealing before discharge for inspection or secondary packing.
The liquid, dose and complete ampoule format are reviewed together. Filling needles, format parts, burner settings, optional gas flushing and line interfaces follow the approved product and sealing requirements; the quotation and machine datasheet define the supplied configuration.
Before ordering
Planning a new ampoule line? Use our ampoule filling and sealing buying guide to prepare glass-format drawings, liquid and dose details, utility requirements and agreed trial checks before requesting a quotation.
Review these details in the quotation and agreed factory acceptance test (FAT) before approving the machine. Published descriptions do not establish one universal dose range, output or included option.
Provide every ampoule sample or drawing, body and neck dimensions, liquid and fill volume. The approved liquid, dosing conditions and seal profile determine the guides, filling needles, dose settings and burner positions.
Specify the required ampoules per minute. Filling time, glass-neck heating and the approved flame-sealing cycle affect the line rate. Agree filling tolerance, seal requirements, inspection scope and the FAT sampling method for the actual ampoule and liquid.
The quotation identifies filling heads, gas and burner utilities, safety controls and downstream interfaces. Pre- or post-gas flushing and inspection integration are configurable; documentation, installation and training are included only as stated in the approved order.
Why this machine
The Ampoule Filling & Sealing Machine is intended for approved open glass ampoules and compatible pharmaceutical or specialty liquids; performance is assessed against the output and acceptance criteria stated for the approved configuration.
Gentle ampoule feeding and positive format control.
Synchronized filling, optional gas flushing and burner safety control.
For the Ampoule Filling & Sealing Machine, the materials and cleanability review follows this product-contact requirement: Product-contact materials, seals, tubing, valves and surface finish are matched to the product and cleaning method in the approved scope.
Ampoule changeover covers the guides, filling needles, dose settings and burner position needed for the approved body, neck and seal profile.
Sealed ampoules discharge for inspection and secondary packing.
Operating process
Open glass ampoules are aligned upright, indexed through precise liquid dosing and then exposed to controlled neck heating and flame sealing in one synchronized process.
Open ampoules are fed gently into format guides and held upright for synchronized movement through the machine.
Filling needles enter or align with the ampoule openings and deliver the programmed liquid dose into each correctly positioned ampoule.
Filled ampoules move through the regulated burner zone, where the glass neck is preheated and closed to form the specified seal.
Completed ampoules leave the sealing station for visual inspection, collection or downstream secondary packing.
Applications & selection
The ampoule filler meters approved pharmaceutical liquids into open glass ampoules and flame-seals each neck under the validated product and container conditions.
Nutraceutical unit-dose ampoules can be considered when the formulation, dose range and thermal exposure during flame sealing have been approved by trials.
Compatible cosmetic serums or actives may be filled into glass ampoules after product-contact, dosing and seal-integrity requirements are confirmed.
Food or beverage products are suitable only when glass-ampoule packaging, hygienic dosing and the heat-sealing process are approved for that formulation.
Oils, chemicals or agrochemicals require a documented compatibility and flammability review before any product is exposed to the ampoule flame-sealing station.
The machine can operate independently or synchronize with ampoule washing, sterilization, inspection, labeling and secondary-packing equipment.
Technical details
| Machine | Ampoule Filling & Sealing Machine |
|---|---|
| Category | Liquid Filling Machines |
| Suitable For | Approved open glass ampoules and compatible pharmaceutical or specialty liquids |
| Working Principle | Ampoules are aligned upright, filled through controlled needles and moved to a regulated preheating and flame-sealing station. |
| Infeed / Handling | Gentle ampoule feeding and positive format control |
| Outfeed / Transfer | Sealed ampoules discharge for inspection and secondary packing |
| Machine Construction | GMP-oriented stainless-steel construction as defined in the approved scope |
|---|---|
| Contact Materials | Product-contact materials, seals, tubing, valves and surface finish are matched to the product and cleaning method in the approved scope. |
| Control System | Synchronized filling, optional gas flushing and burner safety control |
| Changeover | Settings, guides and format parts matched to approved samples or drawings |
| Optional Scope | Pre- and post-gas flushing, number of heads, seal method and inspection integration are configurable. |
| Line Integration | Standalone supply or integration with approved upstream and downstream machines |
| Configuration / Model | Synchronized ampoule liquid filling and flame-sealing machine. The final model code is assigned in the approved quotation. |
|---|---|
| Ampoules / Fill Range | Approved open glass ampoules with compatible pharmaceutical or specialty liquids. Body and neck dimensions, fill volume and required seal profile are agreed from samples. |
| Filling / Sealing Method | Ampoules are held upright, filled through controlled needles, then moved through regulated glass-neck preheating and flame sealing. |
| Heads / Selected Options | Filling-needle count and seal arrangement follow the approved ampoule and output requirement. Pre- or post-gas flushing and inspection integration are optional scope items. |
| Output Evaluation | Evaluate ampoules per minute using the agreed ampoule size, dose, needle count, filling time, neck-heating conditions and flame-sealing cycle. |
| Acceptance / FAT Basis | Fill tolerance, sampling conditions and the required seal profile are agreed for approved ampoule and liquid samples. Filling-and-sealing FAT records can be included in the order. |
| Product Contact / Construction | Dosing parts and needles suit the approved liquid. Ampoule guides, heated-zone parts, guards and gas-path materials are documented for the selected arrangement. |
| Electrical / Burner Utilities | Voltage, phase, frequency and connected load follow the approved load list. Burner and gas services, product feed and any gas-flushing or pneumatic services are agreed before manufacture. |
| Footprint / Line Interfaces | Final length, width and height are stated in the approved GA drawing. Upstream ampoule preparation and downstream inspection, leak testing or collection interfaces follow the ordered line scope. |
| Ampoule Change Parts | Match guides, feed parts, filling needles, dose settings and burner positions to the approved ampoule body, neck, fill volume and seal profile. |
| Warranty | Order-specific. Duration, commencement date, covered parts, exclusions and claim terms are stated in the approved quotation or order. |
| Installation / Commissioning Scope | Order-specific. The quotation states whether installation, commissioning, SAT and operator training are included, together with unloading, positioning, utilities, civil work, trial materials, travel and site responsibilities. |
Final specifications follow the approved quotation, layout, datasheet and project URS.
Options & project scope
Approved open glass ampoules and compatible pharmaceutical or specialty liquids.
Pre- and post-gas flushing, number of heads, seal method and inspection integration are configurable.
Documentation for the Ampoule Filling & Sealing Machine records synchronized filling, optional gas flushing and burner safety control, the confirmed utilities and the agreed acceptance tests; drawings, manuals and qualification records are supplied when ordered.
Controls & protection
Controls, alarms and interfaces are confirmed for the ordered configuration.
Synchronized filling, optional gas flushing and burner safety control.
Infeed readiness: gentle ampoule feeding and positive format control.
Approved transfer: sealed ampoules discharge for inspection and secondary packing.
Configuration-specific: Electrical supply, compressed air, product feed or temperature control, gas or vacuum, and cleaning or CIP interfaces are listed as applicable.
Configuration-specific: Filling tolerance and the FAT sampling method are guaranteed only for the approved product, dose, container and operating conditions.
Pre- and post-gas flushing, number of heads, seal method and inspection integration are configurable.
Related machines
For the format drawings and change parts to review with the selected machine, read the machine change-parts guide.
Frequently asked questions
The Ampoule Filling & Sealing Machine meters liquid into open ampoules and forms a closed glass-neck seal in one synchronized operation.
Suitable products and formats include approved open glass ampoules and compatible pharmaceutical or specialty liquids. Final suitability is confirmed from approved samples, drawings and process details.
Ampoules are aligned upright, filled through controlled needles and moved to a regulated preheating and flame-sealing station.
The Ampoule Filling & Sealing Machine handles material using gentle ampoule feeding and positive format control.
The rated output in ampoules per minute depends on ampoule size, fill volume, number of filling needles, dosing time, glass-neck heating and the validated flame-sealing cycle.
Approved guides, feed parts, filling needles, dose settings and burner positions are matched to the ampoule body, neck, fill volume and required seal profile.
Product-contact dosing parts and filling needles are selected for the approved liquid, while ampoule guides, heated sealing-zone parts, guards and gas-path materials are documented for the chosen configuration.
The available control scope includes synchronized filling, optional gas flushing and burner safety control. Final alarms and interlocks are documented in the approved control specification.
Pre- and post-gas flushing, number of heads, seal method and inspection integration are configurable.
The machine follows ampoule washing and sterilization or depyrogenation, then discharges sealed ampoules to leak testing, visual inspection, labeling or collection as specified.
The package can include ampoule-format drawings, dosing and calibration instructions, burner and gas schematic, utility list, electrical drawings, manuals, layout and filling-and-sealing FAT records.
Please provide the following: ampoule and liquid samples, fill volume, required output, gas and burner utilities, seal requirement and inspection scope.
Contact us
Share your application and required capacity for a quotation.