For approved pharmaceutical glass vials, liquid formulations and compatible rubber stoppers, with controlled vial infeed and synchronized indexing.
Machine overview
H M Pharma Machines manufactures the Automatic Vial Liquid Filling & Rubber Stoppering Machine in Ahmedabad, Gujarat, India for pharmaceutical, nutraceutical, cosmetic, food, chemical and allied production applications.
The Automatic Vial Liquid Filling & Rubber Stoppering Machine uses controlled vial infeed and synchronized indexing for container and product flow. Its approved process completes when stoppered vials discharge toward the capping machine.
Detailed engineering for the Automatic Vial Liquid Filling & Rubber Stoppering Machine aligns no-vial/no-fill and no-stopper logic with optional gas flushing and barrier integration with the approved application, target output, utility schedule and final line layout before the GA drawing is released.
Why this machine
The Automatic Vial Liquid Filling & Rubber Stoppering Machine is intended for approved pharmaceutical glass vials, liquid formulations and compatible rubber stoppers; performance is assessed against the output and acceptance criteria stated for the approved configuration.
Controlled vial infeed and synchronized indexing.
No-vial/no-fill and no-stopper logic with optional gas flushing and barrier integration.
For the Automatic Vial Liquid Filling & Rubber Stoppering Machine, the materials and cleanability review follows this product-contact requirement: Product-contact materials, seals, tubing, valves and surface finish are matched to the product and cleaning method in the approved scope.
Vial changeover covers format guides, filling nozzles, pump settings and the stopper track and insertion parts approved for the selected vial.
Stoppered vials discharge toward the capping machine.
Operating process
Vials are indexed under the filling nozzles for measured dosing, then transferred in sequence to the stopper presentation and insertion station before capping.
Empty vials enter through the format guides and are positively indexed beneath the active filling nozzles.
The selected dosing pump delivers the programmed liquid quantity into each correctly positioned vial.
Compatible rubber stoppers are oriented and presented to the stoppering station in synchronization with the filled vials.
Each stopper is inserted to the specified full or partial position, and the stoppered vial discharges toward the capping machine.
Applications & selection
Pharmaceutical liquids are accurately dosed into approved vials before compatible rubber stoppers are oriented and inserted in sequence.
Nutraceutical preparations are considered only when vial packaging, product-contact materials, dose and stopper requirements suit this machine.
Cosmetic and personal-care liquids require a compatible vial-and-stopper format; ordinary bottles or jars need different handling equipment.
Food and beverage products are suitable only for approved vial packaging and a hygiene process matched to the dosing and stoppering path.
Oils, chemicals or agrochemicals require seal, tubing, pump and stopper compatibility plus a documented safety review before filling.
The vial filling and rubber stoppering machine can link vial preparation to downstream crimp capping, inspection, labeling and collection equipment.
Technical details
| Machine | Automatic Vial Liquid Filling & Rubber Stoppering Machine |
|---|---|
| Category | Liquid Filling Machines |
| Suitable For | Approved pharmaceutical glass vials, liquid formulations and compatible rubber stoppers |
| Working Principle | Vials are indexed below filling nozzles, dosed by the selected pump and transferred directly to an automatic stopper feeding and insertion station. |
| Infeed / Handling | Controlled vial infeed and synchronized indexing |
| Outfeed / Transfer | Stoppered vials discharge toward the capping machine |
| Machine Construction | GMP-oriented stainless-steel construction as defined in the approved scope |
|---|---|
| Contact Materials | Product-contact materials, seals, tubing, valves and surface finish are matched to the product and cleaning method in the approved scope. |
| Control System | No-vial/no-fill and no-stopper logic with optional gas flushing and barrier integration |
| Changeover | Settings, guides and format parts matched to approved samples or drawings |
| Optional Scope | Full or partial stoppering, nitrogen flushing, LAF, RABS or isolator interface can be engineered. |
| Line Integration | Standalone supply or integration with approved upstream and downstream machines |
| Reference scope | HMLS-20 is the published model reference. The 10–100 mL working range, 50–250 mL syringe set and 1000 mL motor/dose note describe different reference attributes, not one continuous qualified vial-filling range. The quotation must separately state approved vial dimensions, liquid fill-volume range, selected syringe/pump, motor and demonstrated filling conditions. |
|---|---|
| Model / Series | Published reference. HMLS-20 |
| Output / Throughput | Configuration-specific. The rated output in containers per minute depends on fill volume, viscosity, temperature, foam, container, dosing technology and number of filling heads. |
| Accuracy / Acceptance Criterion | Published reference. ±1% filling accuracy on a single dose. |
| Electrical Power | Published reference: main machine 1 HP, 415 V, 50 Hz; conveyor 0.5 HP, 415 V, 50 Hz; three-phase + neutral + earth; total listed load 2 kW. The reference additionally notes 1.5 HP for a maximum single dose of 1000 mL. Confirm which motor/dose configuration that note applies to; it does not establish a 1000 mL operating dose for the approved vial machine. |
| Utilities | Published reference. Minimum compressed-air pressure 6 bar; consumption 0.5 CFM. |
| Overall Dimensions (L × W × H) | Published reference. Machine: 2135 × 1150 × 1610 mm; shipping case: 2350 × 1350 × 1650 mm; conveyor height adjustable from 860 to 910 mm. |
| Net / Shipping Weight | Published reference. 600 kg net / 850 kg gross. |
| Capacity / Format Range | Published working-range reference: 10–100 mL with change parts. The quoted reference also lists a 50–250 mL syringe set; syringe-set capacity must not be treated as the qualified fill range or the approved vial size. Confirm vial dimensions, required liquid dose and pump/tooling together. |
| Warranty | Published reference. Manufacturing defects in stainless-steel components are covered; normal wear-and-tear parts, consumables and electrical components are excluded. The quotation does not state a warranty duration. |
| Installation / Commissioning Scope | Published reference. Pre-dispatch operational and maintenance training; buyer may install, or an H M Pharma Machines engineer can attend site with tickets, accommodation, food and local transportation borne by the buyer. |
Final specifications follow the approved quotation, layout, datasheet and project URS.
Options & project scope
Approved pharmaceutical glass vials, liquid formulations and compatible rubber stoppers.
Full or partial stoppering, nitrogen flushing, LAF, RABS or isolator interface can be engineered.
Documentation for the Automatic Vial Liquid Filling & Rubber Stoppering Machine records no-vial/no-fill and no-stopper logic with optional gas flushing and barrier integration, the confirmed utilities and the agreed acceptance tests; drawings, manuals and qualification records are supplied when ordered.
Controls & protection
Controls, alarms and interfaces are confirmed for the ordered configuration.
No-vial/no-fill and no-stopper logic with optional gas flushing and barrier integration.
Infeed readiness: controlled vial infeed and synchronized indexing.
Approved transfer: stoppered vials discharge toward the capping machine.
Published reference: Minimum compressed-air pressure 6 bar; consumption 0.5 CFM.
Published reference: ±1% filling accuracy on a single dose.
Full or partial stoppering, nitrogen flushing, LAF, RABS or isolator interface can be engineered.
Related machines
Use our liquid versus powder vial filling guide to compare dosing, stopper handling and trial requirements, then prepare a quotation brief for the approved product and vial format.
For dosing-method selection using product and container samples, read the liquid filling machine selection guide.
Frequently asked questions
The Automatic Vial Liquid Filling & Rubber Stoppering Machine fills measured liquid doses into vials and promptly places rubber stoppers before the downstream crimping operation.
Suitable products and formats include approved pharmaceutical glass vials, liquid formulations and compatible rubber stoppers. Final suitability is confirmed from approved samples, drawings and process details.
Vials are indexed below filling nozzles, dosed by the selected pump and transferred directly to an automatic stopper feeding and insertion station.
The Automatic Vial Liquid Filling & Rubber Stoppering Machine handles material using controlled vial infeed and synchronized indexing.
The rated output in vials per minute depends on vial size, fill volume and pump cycle, number of filling nozzles, indexing time, stopper-feed capacity and the selected full or partial insertion process.
Vial guides and indexing parts, dosing pump or parts, filling needles, recipe, stopper bowl and insertion tooling are qualified together using approved samples.
The dosing pump, tubing or piping, filling needles and associated seals are specified as product-contact parts, while vial guides and stopper-feed components are defined from approved samples.
The available control scope includes no-vial/no-fill and no-stopper logic with optional gas flushing and barrier integration. Final alarms and interlocks are documented in the approved control specification.
Full or partial stoppering, nitrogen flushing, LAF, RABS or isolator interface can be engineered.
The machine receives prepared empty vials and discharges stoppered vials directly to aluminum-seal crimp capping, with enclosure, gas, line-status and environmental interfaces included where specified.
The order can include vial, dose and stopper format data, dosing calibration, stopper-feed and insertion details, product-contact certificates, electrical, pneumatic and gas diagrams, manuals, layout and FAT protocol.
Please provide the following: vial and stopper samples, formulation, dose range, output, gassing, barrier and validation requirements.
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