1 mL to 20 mL Ampoule Range
The rotary gripper arrangement handles approved ampoule configurations across the specified range.
High-speed ampoule washing machine for 1 mL to 20 mL ampoules, with four output models, mesh-conveyor infeed handling and defined RC/PW/WFI washing stages.
Machine overview
H M Pharma Machines manufactures the Rotary Gripper Ampoule Washing Machine in Ahmedabad, Gujarat, India. It is configured for ampoules from 1 mL to 20 mL.
Ampoules are transferred from the mesh conveyor through the infeed feedworm and infeed starwheel before entering the rotary gripper washing machine. The machine is available in 120 APM, 180 APM, 240 APM and 320 APM models; APM means ampoules per minute.
The process arrangement includes six internal stages in the sequence RC water, air, PW, air, WFI and air. Two external stages apply RC water followed by air. Separate 40 L tanks are provided for RC water, PW and WFI, together with three process pumps, automatic level controls, HMI pressure monitoring and safety interlocks.
Available models
Choose the model according to the required ampoules-per-minute output and approved 1 mL to 20 mL ampoule configuration.
Why this machine
The rotary gripper arrangement handles approved ampoule configurations across the specified range.
Select 120, 180, 240 or 320 APM according to the required production output.
Ampoules transfer through the feedworm and infeed starwheel before entering the machine.
Six internal and two external stages use RC water, PW, WFI and air.
Three 40 L tanks separately serve RC water, PW and WFI.
Tank-level controls, HMI pressure monitoring and utility interlocks protect the washing process.
Ampoule infeed sequence
The ampoule infeed system provides a defined transfer path from bulk loading to the rotary gripper washing section.
Ampoules are loaded and carried forward on the mesh conveyor.
The infeed feedworm spaces and transfers ampoules from the mesh conveyor.
The infeed starwheel receives the spaced ampoules and transfers them toward the machine.
Ampoules enter the rotary gripper washing machine for the defined wash cycle.
Exact wash cycle
Each gripped ampoule passes through the following six internal water and air stages.
Recycled water provides the first internal wash.
An air stage follows the RC water wash.
Purified Water provides the next internal wash.
An air stage follows the PW wash.
Water for Injection provides the final water stage.
The final air stage completes the internal cycle.
Terminology: RC means recycled water, PW means Purified Water and WFI means Water for Injection.
External washing sequence: two stages are provided for the ampoule outer surface.
RC water is applied to the ampoule outer surface.
An air stage follows the external RC water wash.
Technical details
| Ampoule Range | 1 mL to 20 mL |
|---|---|
| Output Models | 120, 180, 240 and 320 APM |
| Output Unit | APM — ampoules per minute |
| Infeed Handling | Mesh conveyor → infeed feedworm → infeed starwheel → machine |
| Internal Stages | 6 |
| Internal Sequence | RC water → air → PW → air → WFI → air |
| External Stages | 2 |
| External Sequence | RC water → air |
| Process Tanks | 3 tanks, 40 L each |
|---|---|
| Tank Services | RC water, PW and WFI |
| Process Pumps | 3 |
| Tank Level Control | High/low sensors with automatic feeding-valve control |
| HMI Pressure Display | RC water, PW, WFI and air pressure |
| Safety Interlocks | Automatic stop for low tank level or loss of required utility pressure |
| Documents | DQ, IQ, OQ & PQ; FAT & SAT; HMI Manual; Operation Manual; serial-matched component TCs; wiring diagram; machine layout |
The 1 mL to 20 mL ampoule range, final model selection, utilities and performance are confirmed against the approved ampoule sample, drawing and washing process.
Process control & protection
The control system monitors the ampoule-washing utilities and protects the process when a required condition is not available.
High and low level sensors are provided in the RC, PW and WFI tanks. When a tank level calls for water, its feeding valve switches on automatically.
If the required inlet water is unavailable and an RC, PW or WFI tank reaches its low-level limit, the machine stops automatically.
Pressure transmitters monitor RC water, PW, WFI and compressed air continuously on the HMI auto screen.
If the required RC water, PW, WFI or air pressure is unavailable, the relevant interlock stops the machine automatically.
Configuration & documents
Select the 120, 180, 240 or 320 APM model according to the required production output.
Ampoule handling and final suitability within the stated range are confirmed from the ampoule sample or drawing.
Ampoules pass through the infeed feedworm and infeed starwheel before entering the machine.
The documentation package includes Design Qualification (DQ), Installation Qualification (IQ), Operational Qualification (OQ), Performance Qualification (PQ), Factory Acceptance Test (FAT) and Site Acceptance Test (SAT) documents, plus the HMI Manual and Operation Manual. Component TCs are matched to serial numbers, and the electrical wiring diagram and machine layout are also supplied.
Related machines
Frequently asked questions
Technical answers covering the 1 mL to 20 mL ampoule range, APM models, mesh-conveyor infeed, RC/PW/WFI sequence, automatic controls and documents.
The machine works with ampoules from 1 mL to 20 mL, subject to the approved ampoule configuration.
The machine is available in four output models: 120 APM, 180 APM, 240 APM and 320 APM.
APM means ampoules per minute and identifies the rated output model.
Ampoules travel from the mesh conveyor into the infeed feedworm, then into the infeed starwheel and finally into the rotary gripper washing machine.
The ampoule washer has six internal washing stages and two external washing stages.
The internal sequence is RC water, air, PW, air, WFI and air.
The two external stages are RC water followed by air.
The washing process uses RC water, PW and WFI, together with air stages.
RC means recycled water, PW means Purified Water and WFI means Water for Injection.
Three 40 L tanks are provided: one each for RC water, PW and WFI.
The process system includes three pumps.
High- and low-level sensors control tank feeding. If the required inlet water is unavailable and an RC, PW or WFI tank reaches its low-level limit, the machine stops automatically.
Pressure transmitters continuously monitor RC-water, PW, WFI and compressed-air pressure on the HMI auto screen. Loss of any required pressure stops the machine automatically.
The supply includes DQ, IQ, OQ and PQ qualification documents; FAT and SAT documents; the HMI Manual and Operation Manual; serial-matched component TCs and certificates; the electrical wiring diagram; and the machine layout.
Share the ampoule size from 1 mL to 20 mL, required APM model, ampoule sample or drawing and washing-process details for a suitable quotation.
Contact us
Contact H M Pharma Machines for model selection, technical discussion and quotation.